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In silico analysis of missense mutations in exons 1–5 of the F9 gene that cause hemophilia B
BACKGROUND: Missense mutations in the first five exons of F9, which encodes factor FIX, represent 40% of all mutations that cause hemophilia B. To address the ongoing debate regarding in silico identification of disease-causing mutations at these exons, we analyzed 215 missense mutations from www.fa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599346/ https://www.ncbi.nlm.nih.gov/pubmed/31253089 http://dx.doi.org/10.1186/s12859-019-2919-x |