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Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells

BACKGROUND: The Warburg effect demonstrates the importance of glycolysis in the development of primary and metastatic cancers. We aimed to explore the role of monocarboxylate transporter 1 (MCT1) and MCT4, two essential transporters of lactate, in renal cancer progression during cancer-endothelial c...

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Detalles Bibliográficos
Autores principales: Guo, Chen, Huang, Tao, Wang, Qing-Hai, Li, Hong, Khanal, Aashish, Kang, En-Hao, Zhang, Wei, Niu, Hai-Tao, Dong, Zhen, Cao, Yan-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599352/
https://www.ncbi.nlm.nih.gov/pubmed/31297034
http://dx.doi.org/10.1186/s12935-019-0889-8