Age-associated Antigen-Presenting Cell Alterations Promote Dry-Eye Inducing Th1 cells

Aging is a significant risk factor for dry eye. Here we used a murine aged mode to investigate the effects of aging on antigen presenting cells (APCs) and generation of pathogenic T helper (Th)1. Our results showed that APCs from aged mice accumulate at the conjunctiva, have higher levels of co-acti...

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Detalles Bibliográficos
Autores principales: Bian, Fang, Xiao, Yangyan, Barbosa, Flavia L., de Souza, Rodrigo G., Hernandez, Humberto, Yu, Zhiyuan, Pflugfelder, Stephen C., de Paiva, Cintia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474/
https://www.ncbi.nlm.nih.gov/pubmed/30696983
http://dx.doi.org/10.1038/s41385-018-0127-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474/
https://www.ncbi.nlm.nih.gov/pubmed/30696983
http://dx.doi.org/10.1038/s41385-018-0127-z

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