LADL: Light-activated dynamic looping for endogenous gene expression control

Mammalian genomes are folded into tens of thousands of long-range looping interactions. The cause and effect relationship between looping and genome function is poorly understood, and the extent to which loops are dynamic on short time scales remains an unanswered question. Here we engineer a new cl...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hun, Rege, Mayuri, Valeri, Jacqueline, Dunagin, Margaret C., Metzger, Aryeh, Titus, Katelyn R., Gilgenast, Thomas G., Gong, Wanfeng, Beagan, Jonathan A., Raj, Arjun, Phillips-Cremins, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599567/
https://www.ncbi.nlm.nih.gov/pubmed/31235883
http://dx.doi.org/10.1038/s41592-019-0436-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599567/
https://www.ncbi.nlm.nih.gov/pubmed/31235883
http://dx.doi.org/10.1038/s41592-019-0436-5

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