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LADL: Light-activated dynamic looping for endogenous gene expression control
Mammalian genomes are folded into tens of thousands of long-range looping interactions. The cause and effect relationship between looping and genome function is poorly understood, and the extent to which loops are dynamic on short time scales remains an unanswered question. Here we engineer a new cl...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599567/ https://www.ncbi.nlm.nih.gov/pubmed/31235883 http://dx.doi.org/10.1038/s41592-019-0436-5 |