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ZnAs@SiO(2) nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling

Rationale: Current therapies for hepatocellular carcinoma (HCC) are hampered by treatment failure and recurrence due to the remaining treatment-resistant liver cancer stem cells (CSCs). Stemness and epithelial-mesenchymal transition (EMT) are regarded as two fundamental characteristics of liver CSCs...

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Detalles Bibliográficos
Autores principales: Huang, Yongquan, Zhou, Bin, Luo, Hui, Mao, Junjie, Huang, Yin, Zhang, Ke, Mei, Chaoming, Yan, Yan, Jin, Hongjun, Gao, Jinhao, Su, Zhongzhen, Pang, Pengfei, Li, Dan, Shan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599649/
https://www.ncbi.nlm.nih.gov/pubmed/31285768
http://dx.doi.org/10.7150/thno.32462