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Controllable Autocatalytic Cleavage-Mediated Fluorescence Recovery for Homogeneous Sensing of Alkyladenine DNA Glycosylase from Human Cancer Cells

DNA alkylation and oxidation are two most common forms of cytotoxic damage with the characteristics of mutagenic and carcinogenic. Human alkyladenine DNA glycosylase (hAAG) is the only glycosylase known to repair a wide variety of alkylative and oxidative DNA lesions. However, few approaches are cap...

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Detalles Bibliográficos
Autores principales: Wang, Li-Juan, Luo, Ming-Li, Yang, Xiao-Yun, Li, Xiao-Fang, Wu, Yanxia, Zhang, Chun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599653/
https://www.ncbi.nlm.nih.gov/pubmed/31285772
http://dx.doi.org/10.7150/thno.35393