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Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-N,N-disubstituted thioureas as versatile substrate

An expedient and tandem regioselective one-pot protocol for the sono-synthesis of bis-[1,2,4]-triazol-3-yl amines and bis-2-iminothiazolines from corresponding bis-1,3-disubstituted thioureas has been developed. The products' regioselectivity correlate well with the pK(a)s of the parent amines,...

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Detalles Bibliográficos
Autores principales: Arafa, Wael Abdelgayed Ahmed, Ibrahim, Hamada Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599792/
https://www.ncbi.nlm.nih.gov/pubmed/31312476
http://dx.doi.org/10.1098/rsos.181963