Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption by suppressing MAPK, NF-κB and AKT signalling pathways and promotes Caspase3-mediated apoptosis of mature osteoclasts

Osteoclasts are multinuclear giant cells that have unique ability to degrade bone. The search for new medicines that modulate the formation and function of osteoclasts is a potential approach for treating osteoclast-related bone diseases. Piceatannol (PIC) is a natural organic polyphenolic stilbene...

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Detalles Bibliográficos
Autores principales: Yan, Liuliu, Lu, Lulu, Hu, Fangbin, Shetti, Dattatrya, Wei, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Cellular and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599799/
https://www.ncbi.nlm.nih.gov/pubmed/31312498
http://dx.doi.org/10.1098/rsos.190360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599799/
https://www.ncbi.nlm.nih.gov/pubmed/31312498
http://dx.doi.org/10.1098/rsos.190360

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