PARP1 expression in soft tissue sarcomas is a poor‐prognosis factor and a new potential therapeutic target

Soft tissue sarcomas (STSs) are aggressive tumors with few efficient systemic therapies. Poly(ADP‐ribose) polymerase‐1 (PARP1) inhibitors represent an emerging therapeutic option in tumors with genomic instability. The genomics of STSs is complex in more than half of cases, suggesting a high level o...

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Detalles Bibliográficos
Autores principales: Bertucci, François, Finetti, Pascal, Monneur, Audrey, Perrot, Delphine, Chevreau, Christine, Le Cesne, Axel, Blay, Jean‐Yves, Mir, Olivier, Birnbaum, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599836/
https://www.ncbi.nlm.nih.gov/pubmed/31131495
http://dx.doi.org/10.1002/1878-0261.12522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599836/
https://www.ncbi.nlm.nih.gov/pubmed/31131495
http://dx.doi.org/10.1002/1878-0261.12522

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