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Negative regulation of miR‐1275 by H3K27me3 is critical for glial induction of glioblastoma cells

Activation of the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway induces glial differentiation of glioblastoma (GBM) cells, but the mechanism by which microRNA (miRNA) regulate this process remains poorly understood. In this study, by performing miRNA genomics and loss‐ and gain‐...

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Detalles Bibliográficos
Autores principales: Mai, Jialuo, Gu, Jiayu, Liu, Ying, Liu, Xincheng, Sai, Ke, Chen, Zhijie, Lu, Wanjun, Yang, Xiaozhi, Wang, Jingyi, Guo, Cui, Sun, Shuxin, Xing, Fan, Sheng, Longxiang, Lu, Bingzheng, Zhu, Zhu, Sun, Hongjiaqi, Xue, Dongdong, Lin, Yuan, Cai, Jing, Tan, Yaqian, Li, Chuntao, Yin, Wei, Cao, Lin, Ou‐yang, Ying, Qiu, Pengxin, Su, Xingwen, Yan, Guangmei, Liang, Jiankai, Zhu, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599839/
https://www.ncbi.nlm.nih.gov/pubmed/31162799
http://dx.doi.org/10.1002/1878-0261.12525