Identification of an Alternating-Access Dynamics Mutant of EmrE with Impaired Transport

Proteins that perform active transport must alternate the access of a binding site, first to one side of a membrane and then to the other, resulting in the transport of bound substrates across the membrane. To better understand this process, we sought to identify mutants of the small multidrug resis...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Wynne, Samantha A., Thomas, Nathan E., Uhlemann, Eva-Maria, Tate, Christopher G., Henzler-Wildman, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599891/
https://www.ncbi.nlm.nih.gov/pubmed/31158365
http://dx.doi.org/10.1016/j.jmb.2019.05.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599891/
https://www.ncbi.nlm.nih.gov/pubmed/31158365
http://dx.doi.org/10.1016/j.jmb.2019.05.035

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