Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis

Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis and fatty infiltrations. Here we show that the NOTCH pathway negatively modulates FAP differentiation both in vitro...

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Detalles Bibliográficos
Autores principales: Marinkovic, Milica, Fuoco, Claudia, Sacco, Francesca, Cerquone Perpetuini, Andrea, Giuliani, Giulio, Micarelli, Elisa, Pavlidou, Theodora, Petrilli, Lucia Lisa, Reggio, Alessio, Riccio, Federica, Spada, Filomena, Vumbaca, Simone, Zuccotti, Alessandro, Castagnoli, Luisa, Mann, Matthias, Gargioli, Cesare, Cesareni, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599969/
https://www.ncbi.nlm.nih.gov/pubmed/31239312
http://dx.doi.org/10.26508/lsa.201900437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599969/
https://www.ncbi.nlm.nih.gov/pubmed/31239312
http://dx.doi.org/10.26508/lsa.201900437

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