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Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis and fatty infiltrations. Here we show that the NOTCH pathway negatively modulates FAP differentiation both in vitro...
Autores principales: | Marinkovic, Milica, Fuoco, Claudia, Sacco, Francesca, Cerquone Perpetuini, Andrea, Giuliani, Giulio, Micarelli, Elisa, Pavlidou, Theodora, Petrilli, Lucia Lisa, Reggio, Alessio, Riccio, Federica, Spada, Filomena, Vumbaca, Simone, Zuccotti, Alessandro, Castagnoli, Luisa, Mann, Matthias, Gargioli, Cesare, Cesareni, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599969/ https://www.ncbi.nlm.nih.gov/pubmed/31239312 http://dx.doi.org/10.26508/lsa.201900437 |
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