Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor–based immunotherapy

NADPH oxidases catalyze the production of reactive oxygen species and are involved in physio/pathological processes. NOX1 is highly expressed in colon cancer and promotes tumor growth. To investigate the efficacy of NOX1 inhibition as an anticancer strategy, tumors were grown in immunocompetent, imm...

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Detalles Bibliográficos
Autores principales: Stalin, Jimmy, Garrido-Urbani, Sarah, Heitz, Freddy, Szyndralewiez, Cédric, Jemelin, Stephane, Coquoz, Oriana, Ruegg, Curzio, Imhof, Beat A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599972/
https://www.ncbi.nlm.nih.gov/pubmed/31249132
http://dx.doi.org/10.26508/lsa.201800265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599972/
https://www.ncbi.nlm.nih.gov/pubmed/31249132
http://dx.doi.org/10.26508/lsa.201800265

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