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Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor–based immunotherapy
NADPH oxidases catalyze the production of reactive oxygen species and are involved in physio/pathological processes. NOX1 is highly expressed in colon cancer and promotes tumor growth. To investigate the efficacy of NOX1 inhibition as an anticancer strategy, tumors were grown in immunocompetent, imm...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599972/ https://www.ncbi.nlm.nih.gov/pubmed/31249132 http://dx.doi.org/10.26508/lsa.201800265 |