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The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs

Tumors of different molecular subtypes can show strongly deviating responses to drug treatment, making stratification of patients based on molecular markers an important part of cancer therapy. Pharmacogenomic studies have led to the discovery of selected genomic markers (e.g., BRAF(V600E)), whereas...

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Detalles Bibliográficos
Autores principales: Rydenfelt, Mattias, Wongchenko, Matthew, Klinger, Bertram, Yan, Yibing, Blüthgen, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600015/
https://www.ncbi.nlm.nih.gov/pubmed/31253656
http://dx.doi.org/10.26508/lsa.201900445