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MOV10L1 Binds RNA G-Quadruplex in a Structure-Specific Manner and Resolves It More Efficiently Than MOV10

MOV10L1 and its paralog MOV10 are evolutionally conserved RNA helicases involved in distinct RNA regulatory pathways. The testis-specific MOV10L1 is essential for spermatogenesis and PIWI-interacting RNAs biogenesis, whereas MOV10 is ubiquitous and multifunctional. Although both proteins have been i...

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Detalles Bibliográficos
Autores principales: Zhang, Xia, Yu, Lina, Ye, Shasha, Xie, Jie, Huang, Xingxu, Zheng, Ke, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600044/
https://www.ncbi.nlm.nih.gov/pubmed/31252377
http://dx.doi.org/10.1016/j.isci.2019.06.016