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Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway

Context: Shikonins, a series of natural occurring naphthoquinones extracted from Arnebia euchroma (Royle) Jonst. (Boraginaceae), have antitumor activities and low toxicity. Objective: To illuminate potential activity and mechanism of shikonins against colorectal cancer (CRC). Materials and methods:...

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Detalles Bibliográficos
Autores principales: Zhu, Yuzhen, Zhong, Yu, Long, Xun, Zhu, Zhu, Zhou, Yu, Ye, Hua, Zeng, Xiaobin, Zheng, Xuebao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600065/
https://www.ncbi.nlm.nih.gov/pubmed/31230505
http://dx.doi.org/10.1080/13880209.2019.1626447