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Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway
Context: Shikonins, a series of natural occurring naphthoquinones extracted from Arnebia euchroma (Royle) Jonst. (Boraginaceae), have antitumor activities and low toxicity. Objective: To illuminate potential activity and mechanism of shikonins against colorectal cancer (CRC). Materials and methods:...
Autores principales: | Zhu, Yuzhen, Zhong, Yu, Long, Xun, Zhu, Zhu, Zhou, Yu, Ye, Hua, Zeng, Xiaobin, Zheng, Xuebao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600065/ https://www.ncbi.nlm.nih.gov/pubmed/31230505 http://dx.doi.org/10.1080/13880209.2019.1626447 |
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