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Noggin depletion in adipocytes promotes obesity in mice

OBJECTIVE: Obesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin is largely unknown. The aim of the study was...

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Detalles Bibliográficos
Autores principales: Blázquez-Medela, Ana M., Jumabay, Medet, Rajbhandari, Prashant, Sallam, Tamer, Guo, Yina, Yao, Jiayi, Vergnes, Laurent, Reue, Karen, Zhang, Li, Yao, Yucheng, Fogelman, Alan M., Tontonoz, Peter, Lusis, Aldons J., Wu, Xiuju, Boström, Kristina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600080/
https://www.ncbi.nlm.nih.gov/pubmed/31027994
http://dx.doi.org/10.1016/j.molmet.2019.04.004