Cargando…

JUND regulates pancreatic β cell survival during metabolic stress

OBJECTIVE: In type 2 diabetes (T2D), oxidative stress contributes to the dysfunction and loss of pancreatic β cells. A highly conserved feature of the cellular response to stress is the regulation of mRNA translation; however, the genes regulated at the level of translation are often overlooked due...

Descripción completa

Detalles Bibliográficos
Autores principales: Good, Austin L., Cannon, Corey E., Haemmerle, Matthew W., Yang, Juxiang, Stanescu, Diana E., Doliba, Nicolai M., Birnbaum, Morris J., Stoffers, Doris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600134/
https://www.ncbi.nlm.nih.gov/pubmed/31023625
http://dx.doi.org/10.1016/j.molmet.2019.04.007