RTA 408 Inhibits Interleukin-1β-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent NF-κB and AP-1 Activation in Rat Brain Astrocytes

Neuroinflammation is characterized by the elevated expression of various inflammatory proteins, including matrix metalloproteinases (MMPs), induced by various pro-inflammatory mediators, which play a critical role in neurodegenerative disorders. Interleukin-1β (IL-1β) has been shown to induce the up...

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Detalles Bibliográficos
Autores principales: Yang, Chien-Chung, Lin, Chih-Chung, Jou, Mei-Jie, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600142/
https://www.ncbi.nlm.nih.gov/pubmed/31185608
http://dx.doi.org/10.3390/ijms20112826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600142/
https://www.ncbi.nlm.nih.gov/pubmed/31185608
http://dx.doi.org/10.3390/ijms20112826

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