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RTA 408 Inhibits Interleukin-1β-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent NF-κB and AP-1 Activation in Rat Brain Astrocytes
Neuroinflammation is characterized by the elevated expression of various inflammatory proteins, including matrix metalloproteinases (MMPs), induced by various pro-inflammatory mediators, which play a critical role in neurodegenerative disorders. Interleukin-1β (IL-1β) has been shown to induce the up...
Autores principales: | Yang, Chien-Chung, Lin, Chih-Chung, Jou, Mei-Jie, Hsiao, Li-Der, Yang, Chuen-Mao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600142/ https://www.ncbi.nlm.nih.gov/pubmed/31185608 http://dx.doi.org/10.3390/ijms20112826 |
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