Inhibitory Effects of Diketopiperazines from Marine-Derived Streptomyces puniceus on the Isocitrate Lyase of Candida albicans

The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase, and plays an important role in the pathogenesis of microorganisms during infection. An icl-deletion mutant of Candida albicans exhibited reduced virulence in mice comp...

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Detalles Bibliográficos
Autores principales: Kim, Heegyu, Hwang, Ji-Yeon, Shin, Jongheon, Oh, Ki-Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600163/
https://www.ncbi.nlm.nih.gov/pubmed/31167388
http://dx.doi.org/10.3390/molecules24112111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600163/
https://www.ncbi.nlm.nih.gov/pubmed/31167388
http://dx.doi.org/10.3390/molecules24112111

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