A Simple HPLC Method for the Quantitative Determination of Silybin in Rat Plasma: Application to a Comparative Pharmacokinetic Study on Commercial Silymarin Products

Silybin (SBN) is a major active constituent of silymarin, a mixture of flavonoids found in fruits and seeds of milk thistle. The aim of this study was to describe a simple bioanalytical method for quantifying SBN in rat plasma. A simple protein deproteinization procedure with acetonitrile (ACN) was...

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Detalles Bibliográficos
Autores principales: Ha, Eun-Sol, Han, Dong-Gyun, Seo, Seong-Wook, Kim, Ji-Min, Lee, Seon-Kwang, Sim, Woo-Yong, Yoon, In-Soo, Kim, Min-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600178/
https://www.ncbi.nlm.nih.gov/pubmed/31185663
http://dx.doi.org/10.3390/molecules24112180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600178/
https://www.ncbi.nlm.nih.gov/pubmed/31185663
http://dx.doi.org/10.3390/molecules24112180

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