A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs

G protein-coupled receptors (GPCRs) play a key role in many cellular signaling mechanisms, and must select among multiple coupling possibilities in a ligand-specific manner in order to carry out a myriad of functions in diverse cellular contexts. Much has been learned about the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Plante, Ambrose, Shore, Derek M., Morra, Giulia, Khelashvili, George, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600179/
https://www.ncbi.nlm.nih.gov/pubmed/31159491
http://dx.doi.org/10.3390/molecules24112097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600179/
https://www.ncbi.nlm.nih.gov/pubmed/31159491
http://dx.doi.org/10.3390/molecules24112097

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