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A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs
G protein-coupled receptors (GPCRs) play a key role in many cellular signaling mechanisms, and must select among multiple coupling possibilities in a ligand-specific manner in order to carry out a myriad of functions in diverse cellular contexts. Much has been learned about the molecular mechanisms...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600179/ https://www.ncbi.nlm.nih.gov/pubmed/31159491 http://dx.doi.org/10.3390/molecules24112097 |