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Estrogen Receptor Positive Breast Cancer with High Expression of Androgen Receptor has Less Cytolytic Activity and Worse Response to Neoadjuvant Chemotherapy but Better Survival

Estrogen receptor (ER) positive breast cancer (BC), the most abundant BC subtype, is notorious for poor response to neoadjuvant chemotherapy (NAC). The androgen receptor (AR) was reported to support estradiol-mediated ER activity in an in vitro system. Recently, ER-positive BC with fewer tumor infil...

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Detalles Bibliográficos
Autores principales: Okano, Maiko, Oshi, Masanori, Butash, Ali Linsk, Asaoka, Mariko, Katsuta, Eriko, Peng, Xuan, Qi, Qianya, Yan, Li, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600230/
https://www.ncbi.nlm.nih.gov/pubmed/31151151
http://dx.doi.org/10.3390/ijms20112655