The Evolving Role of CD8(+)CD28(−) Immunosenescent T Cells in Cancer Immunology

Functional, tumor-specific CD8(+) cytotoxic T lymphocytes drive the adaptive immune response to cancer. Thus, induction of their activity is the ultimate aim of all immunotherapies. Success of anti-tumor immunotherapy is precluded by marked immunosuppression in the tumor microenvironment (TME) leadi...

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Detalles Bibliográficos
Autores principales: Huff, Wei X., Kwon, Jae Hyun, Henriquez, Mario, Fetcko, Kaleigh, Dey, Mahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600236/
https://www.ncbi.nlm.nih.gov/pubmed/31181772
http://dx.doi.org/10.3390/ijms20112810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600236/
https://www.ncbi.nlm.nih.gov/pubmed/31181772
http://dx.doi.org/10.3390/ijms20112810

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