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The Evolving Role of CD8(+)CD28(−) Immunosenescent T Cells in Cancer Immunology

Functional, tumor-specific CD8(+) cytotoxic T lymphocytes drive the adaptive immune response to cancer. Thus, induction of their activity is the ultimate aim of all immunotherapies. Success of anti-tumor immunotherapy is precluded by marked immunosuppression in the tumor microenvironment (TME) leadi...

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Detalles Bibliográficos
Autores principales:	Huff, Wei X., Kwon, Jae Hyun, Henriquez, Mario, Fetcko, Kaleigh, Dey, Mahua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600236/ https://www.ncbi.nlm.nih.gov/pubmed/31181772 http://dx.doi.org/10.3390/ijms20112810

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