Identification and Structure-Activity Studies of 1,3-Dibenzyl-2-aryl imidazolidines as Novel Hsp90 Inhibitors

Hsp90 (Heat shock protein 90) is involved in various processes in cancer occurrence and development, and therefore represents a promising drug target for cancer therapy. In this work, a virtual screening strategy was employed, leading to the identification of a series of compounds bearing a scaffold...

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Detalles Bibliográficos
Autores principales: Liu, Yajun, Liu, Xiaoxia, Li, Lihong, Dai, Rui, Shi, Meiyun, Xue, Hongyu, Liu, Yong, Wang, Hecheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600241/
https://www.ncbi.nlm.nih.gov/pubmed/31163701
http://dx.doi.org/10.3390/molecules24112105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600241/
https://www.ncbi.nlm.nih.gov/pubmed/31163701
http://dx.doi.org/10.3390/molecules24112105

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