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Conformational Studies of Glucose Transporter 1 (GLUT1) as an Anticancer Drug Target
Glucose transporter 1 (GLUT1) is a facilitative glucose transporter overexpressed in various types of tumors; thus, it has been considered as an important target for cancer therapy. GLUT1 works through conformational switching from an outward-open (OOP) to an inward-open (IOP) conformation passing t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600248/ https://www.ncbi.nlm.nih.gov/pubmed/31181707 http://dx.doi.org/10.3390/molecules24112159 |