Design, Synthesis and Anti-Platelet Aggregation Activity Study of Ginkgolide-1,2,3-triazole Derivatives

Ginkgolides are the major active component of Ginkgo biloba for inhibition of platelet activating factor receptor. An azide-alkyne Huisgen cycloaddition reaction was used to introduce a triazole nucleus into the target ginkgolide molecules. A series of ginkgolide-1,2,3-triazole conjugates with varie...

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Detalles Bibliográficos
Autores principales: Cui, Jian, Hu, Le’An, Shi, Wei, Cui, Guozhen, Zhang, Xumu, Zhang, Qing-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600273/
https://www.ncbi.nlm.nih.gov/pubmed/31181694
http://dx.doi.org/10.3390/molecules24112156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600273/
https://www.ncbi.nlm.nih.gov/pubmed/31181694
http://dx.doi.org/10.3390/molecules24112156

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