Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding

Chromosome ends are transcribed into long noncoding telomeric repeat-containing RNA (TERRA) from subtelomeric promoters. A class of TERRA promoters are associated with CpG islands embedded in repetitive DNA tracts. Cytosines in these subtelomeric CpG islands are frequently methylated in telomerase-p...

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Detalles Bibliográficos
Autores principales: Le Berre, Gabriel, Hossard, Virginie, Riou, Jean-Francois, Guieysse-Peugeot, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600276/
https://www.ncbi.nlm.nih.gov/pubmed/31181625
http://dx.doi.org/10.3390/ijms20112791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600276/
https://www.ncbi.nlm.nih.gov/pubmed/31181625
http://dx.doi.org/10.3390/ijms20112791

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