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Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding
Chromosome ends are transcribed into long noncoding telomeric repeat-containing RNA (TERRA) from subtelomeric promoters. A class of TERRA promoters are associated with CpG islands embedded in repetitive DNA tracts. Cytosines in these subtelomeric CpG islands are frequently methylated in telomerase-p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600276/ https://www.ncbi.nlm.nih.gov/pubmed/31181625 http://dx.doi.org/10.3390/ijms20112791 |