Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

Platelet interaction with collagens, via von Willebrand factor, is a potent trigger of shear-dependent thrombus formation mediated by subsequent engagement of the signaling collagen receptor glycoprotein (GP)VI, enforced by integrin α(2)β(1). Protein tyrosine kinase Syk is central in the GPVI-induce...

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Detalles Bibliográficos
Autores principales: Jooss, Natalie J., De Simone, Ilaria, Provenzale, Isabella, Fernández, Delia I., Brouns, Sanne L.N., Farndale, Richard W., Henskens, Yvonne M.C., Kuijpers, Marijke J.E., ten Cate, Hugo, van der Meijden, Paola E.J., Cavill, Rachel, Heemskerk, Johan W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600290/
https://www.ncbi.nlm.nih.gov/pubmed/31181592
http://dx.doi.org/10.3390/ijms20112788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600290/
https://www.ncbi.nlm.nih.gov/pubmed/31181592
http://dx.doi.org/10.3390/ijms20112788

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