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Structural and Conformational Studies on Carboxamides of 5,6-Diaminouracils—Precursors of Biologically Active Xanthine Derivatives

8-Arylethynylxanthine derivatives are potent, selective adenosine A(2A) receptor antagonists, which represent (potential) therapeutics for Parkinson’s disease, Alzheimer’s dementia, and the immunotherapy of cancer. 6-Amino-5-amidouracil derivatives are important precursors for the synthesis of such...

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Detalles Bibliográficos
Autores principales: Marx, Daniel, Schnakenburg, Gregor, Grimme, Stefan, Müller, Christa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600361/
https://www.ncbi.nlm.nih.gov/pubmed/31181839
http://dx.doi.org/10.3390/molecules24112168