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Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma

Glioblastoma (GBM) is an extremely aggressive tumor of the central nervous system, with a prognosis of 12–15 months and just 3–5% of survival over 5 years. This is mainly because most patients suffer recurrence after treatment that currently consists in maximal resection followed by radio- and chemo...

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Detalles Bibliográficos
Autores principales: Fedele, Monica, Cerchia, Laura, Pegoraro, Silvia, Sgarra, Riccardo, Manfioletti, Guidalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600373/
https://www.ncbi.nlm.nih.gov/pubmed/31167470
http://dx.doi.org/10.3390/ijms20112746