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Novel pH Selective, Highly Lytic Peptides Based on a Chimeric Influenza Hemagglutinin Peptide/Cell Penetrating Peptide Motif

Delivery of macromolecular cargos such as siRNA to the cytosol after endocytosis remains a critical challenge. Numerous approaches including viruses, lipid nanoparticles, polymeric constructs, and various peptide-based approaches have yet to yield a general solution to this delivery issue. In this m...

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Detalles Bibliográficos
Autores principales: Algayer, Bethany, O’Brien, Ann, Momose, Aaron, Murphy, Dennis J., Procopio, William, Tellers, David M., Tucker, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600388/
https://www.ncbi.nlm.nih.gov/pubmed/31159194
http://dx.doi.org/10.3390/molecules24112079