Pharmacokinetics and Tissue Distribution of a Novel Bis-Chelated Gold(I) Diphosphine Compound, Bis(2,3-bis(tert-butylmethylphosphino)Quinoxaline)Aurate(I), in Rats

GC20, a novel soluble bis-chelated gold(I)−diphosphine compound, has been reported as a promising anticancer candidate. Assessing the pharmacokinetic properties of GC20 is critical for its medicinal evaluation. First, a sensitive and specific liquid chromatography tandem mass spectrometry (LC-MS/MS)...

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Detalles Bibliográficos
Autores principales: Peng, Ying, Qi, Huanhuan, Chang, Qingqing, Zhang, Yu, Liu, Weiyi, Liu, Minyu, Liu, Quanhai, Wang, Guangji, Sun, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600414/
https://www.ncbi.nlm.nih.gov/pubmed/31159257
http://dx.doi.org/10.3390/molecules24112082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600414/
https://www.ncbi.nlm.nih.gov/pubmed/31159257
http://dx.doi.org/10.3390/molecules24112082

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