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Stabilization of Intrinsically Disordered DKK2 Protein by Fusion to RNA-Binding Domain
Intrinsic disorders are a common feature of hub proteins in eukaryotic interactomes controlling the signaling pathways. The intrinsically disordered proteins (IDPs) are prone to misfolding, and maintaining their functional stability remains a major challenge in validating their therapeutic potential...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600415/ https://www.ncbi.nlm.nih.gov/pubmed/31212691 http://dx.doi.org/10.3390/ijms20112847 |