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Gastric Leptin and Tumorigenesis: Beyond Obesity
Leptin, an adipocyte-derived hormone and its receptor (ObR) expressed in the hypothalamus are well known as an essential regulator of appetite and energy expenditure. Obesity induces abundant leptin production, however, reduced sensitivity to leptin leads to the development of metabolic disorders, s...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600422/ https://www.ncbi.nlm.nih.gov/pubmed/31141984 http://dx.doi.org/10.3390/ijms20112622 |