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Gene Expression Indicates Altered Immune Modulation and Signaling Pathway Activation in Ovarian Cancer Patients Resistant to Topotecan

Epithelial ovarian cancer (EOC) is one of the deadliest gynecological malignancies. Topotecan remains an essential tool in second-line therapy; even so, most patients develop resistance within a short period of time. We aimed to identify biomarkers of topotecan resistance by using gene expression si...

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Detalles Bibliográficos
Autores principales: Menyhárt, Otília, Fekete, János Tibor, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600443/
https://www.ncbi.nlm.nih.gov/pubmed/31195594
http://dx.doi.org/10.3390/ijms20112750