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Cognitive Impairment That Is Induced by (R)-Ketamine Is Abolished in NMDA GluN2D Receptor Subunit Knockout Mice

Although the N-methyl-D-aspartate receptor antagonist ketamine has attracted attention because of its rapid and sustained antidepressant effects in depressed patients, its side effects have raised some concerns. Ketamine is a racemic mixture of equal amounts of the enantiomers (R)-ketamine and (S)-k...

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Detalles Bibliográficos
Autores principales: Ide, Soichiro, Ikekubo, Yuiko, Mishina, Masayoshi, Hashimoto, Kenji, Ikeda, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600477/
https://www.ncbi.nlm.nih.gov/pubmed/31135879
http://dx.doi.org/10.1093/ijnp/pyz025