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RASSF1A controls tissue stiffness and cancer stem‐like cells in lung adenocarcinoma

Lung cancer remains the leading cause of cancer‐related death due to poor treatment responses and resistance arising from tumour heterogeneity. Here, we show that adverse prognosis associated with epigenetic silencing of the tumour suppressor RASSF1A is due to increased deposition of extracellular m...

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Detalles Bibliográficos
Autores principales: Pankova, Daniela, Jiang, Yanyan, Chatzifrangkeskou, Maria, Vendrell, Iolanda, Buzzelli, Jon, Ryan, Anderson, Brown, Cameron, O'Neill, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600643/
https://www.ncbi.nlm.nih.gov/pubmed/31268606
http://dx.doi.org/10.15252/embj.2018100532