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In Silico Identification of Potential Inhibitor Against a Fungal Histone Deacetylase, RPD3 from Magnaporthe Oryzae

Histone acetylation and deacetylation play an essential role in the epigenetic regulation of gene expression. Histone deacetylases (HDAC) are a group of zinc-binding metalloenzymes that catalyze the removal of acetyl moieties from lysine residues from histone tails. These enzymes are well known for...

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Detalles Bibliográficos
Autores principales: Shanmugam, Gnanendra, Kim, Taehyeon, Jeon, Junhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600661/
https://www.ncbi.nlm.nih.gov/pubmed/31151320
http://dx.doi.org/10.3390/molecules24112075