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Tumor Site-Dependent Transport Properties Determine Nanotherapeutics Delivery and Its Efficacy
Insufficient delivery of systemically administered anticancer drugs to tumors can compromise therapeutic efficacy and develop drug delivery-based therapeutic resistance. Nanotherapeutics such as PEGylated liposomal doxorubicin (PLD) are designed to preferentially accumulate in tumors utilizing enhan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600803/ https://www.ncbi.nlm.nih.gov/pubmed/31228770 http://dx.doi.org/10.1016/j.tranon.2019.05.011 |