Cargando…

Thymoquinone-Induced Tristetraprolin Inhibits Tumor Growth and Metastasis through Destabilization of MUC4 mRNA

Tristetraprolin (TTP), a well-characterized AU-rich element (ARE) binding protein, functions as a tumor suppressor gene. The purpose of this study was to investigate whether a bioactive substance derived from a natural medicinal plant affects the induction of TTP and to elucidate its mechanism. We e...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Se-Ra, Mun, Jeong-Yeon, Jeong, Mi-So, Lee, Hyun-Hee, Roh, Yun-Gil, Kim, Won-Tae, Kim, Min-Hye, Heo, Jeonghoon, Choi, Yung Hyun, Kim, Su Jin, Cha, Hee-Jae, Jun, Mira, Leem, Sun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600862/
https://www.ncbi.nlm.nih.gov/pubmed/31141941
http://dx.doi.org/10.3390/ijms20112614