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Thymoquinone-Induced Tristetraprolin Inhibits Tumor Growth and Metastasis through Destabilization of MUC4 mRNA
Tristetraprolin (TTP), a well-characterized AU-rich element (ARE) binding protein, functions as a tumor suppressor gene. The purpose of this study was to investigate whether a bioactive substance derived from a natural medicinal plant affects the induction of TTP and to elucidate its mechanism. We e...
Autores principales: | Lee, Se-Ra, Mun, Jeong-Yeon, Jeong, Mi-So, Lee, Hyun-Hee, Roh, Yun-Gil, Kim, Won-Tae, Kim, Min-Hye, Heo, Jeonghoon, Choi, Yung Hyun, Kim, Su Jin, Cha, Hee-Jae, Jun, Mira, Leem, Sun-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600862/ https://www.ncbi.nlm.nih.gov/pubmed/31141941 http://dx.doi.org/10.3390/ijms20112614 |
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